3-D Modeling of Proteins

Lecture notes for PABIO-536

Instructor:

Christophe Verlinde
Biomolecular Structure Center
HSB Room K-428A
phone: 3-8865
e-mail: verlinde@u.washington.edu

Contents

  1. Basic Elements of 3D Protein Structure
    1. The Peptide Unit
    2. 3D aspects of Secondary Structure
    3. From 3D Motifs to Multimeric Proteins
  2. Experimental 3D Protein Structures
    1. Structure Determination
    2. The Protein Data Bank
    3. Example of a PDB File
  3. Looking at 3D Structures
    1. 3D Viewers
    2. Organized Collections
  4. Threading: From Sequence to 3D Fold
    1. Threading: Principles
    2. Threading: Servers and Freeware
    3. Threading: Example
  5. From sequence to 3D model: Comparative Modeling
    1. Comparative Modeling: Principles
    2. Comparative Modeling: Servers and Freeware
    3. Comparative Modeling: Example
    4. Comparative Modeling: Model Validation

© Copyright 1997,2002 Christophe Verlinde