- CONJ 545: Molecular interactions and Medicine
- Organizer: C. Verlinde
- Description:
Molecular interactions and Medicine.This course aims to provide a basic
understanding of the various forces governing molecular interactions in
biology, with a focus on medicine. In addition, students will be introduced
to the principles of computer modeling techniques that are in use for predicting
the molecular behaviour of proteins, ligands and their complexes. The power
of these techniques will then be illustrated in terms of in computro ligand
discovery, drug design, and the understanding at the atomic level of some
genetic diseases. Practical experience will be gained during two computer
lab sessions.
- Credits: 1.5
- Offered: Spring.
- BSTR 520: Structure Based Design of Drugs and Vaccines
- Organizers: W. Hol and C. Verlinde
- Description:
Lecture and discussion on research papers illustrating protein structure
based design of new drugs and vaccines. Review of methods of structure-based
drug design and the problem of drug resistance.
- Credits: 3
- Offered: Every other year in winter.
- PABIO 536: Bioinformatics and Gene Sequence Analysis
- Organizer: T. Rose
- Own contribution: 1 lecture.
- Description:
Discussion of nature and relevance of biological sequence information,
current techniques for determining protein and DNA sequences, computer-based
analysis, archival and retrieval of sequence information, available biological
and biochemical databases, and methods for database accession and interrogation.
Credit/no credit only. Prerequisite: biochemistry, molecular biology, and
permission of instructor.
- Credits: 3
- Offered: Winter.
- Handout: 3-D Modeling of Proteins