Res. #: .....150.......16--0.......170..-.....180.......190.......200.......210.......22 FbG_Hu: VQIHDITGKDCQDIANK--GAKQSGLYFIKPL-KANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLS FbH_Hu: VQIHDITGKDCQDIANK--GAKQSGLYFIKPL-KANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLS FbG_Bo: VKIHDVTGRDCQDVANK--GAKESGLYFIRPL-KA-KQFLVYCEIDGSGNGWTVFQKRLDGSLDFKKNWIQYKEGFGHLS FbG_Rt: VRIYDITGKDCQDTANK--GAKESGLYSIRPL-KATEQSLVYCETDGPGNGWTEFKKRLDGSVDFLKNWIQYKEGFGHLS FbG_Xe: VQIQEFTGKDCQEVANK--GARLSGLYYIKPL-KAKQQFLVYCEIEPSGSAWTVIQRRLDGSVNFHKNWVQYREGFGYLS FbG_SL: NKISPITGKDCQQVVDN--GGKDSGLYYIKPL-KAKQPFLVFCEIE-NGNGWTVIQHRHDGSVNFTRDWVSYREGFGYLA FbB_Hu: CNIPVVSGKECEEIIRK--GGETSEMYLIQPD-SSVKPYRVYCDMNTENGGWTVIQNRQDGSVDFGRKWDPYKQGFGNVA FbB_Rt: CNIPVVSGKECEEIIRK--GGETSEMYLIQPD-TSSKPYRVYCDMKTENGGWTVIQNRQDGSVDFGRKWDPYKKGFGNIA FbB_Bo: CNIPVVSGKECEKIIRN--EGETSEMYLIQPE-DSSKPYRVYCDMKTEKGGWTVIQNRQDGSLDFGRKWDPYKQGFGNIA FbB_Ck: CNIPVVSGRECEDIYRK--GGETSEMYIIQPD-PFTTPYRVYCDMETDNGGWTLIQNRQDGSVNFGRAWDEYKRGFGNIA FbB_SL: CRVPVVSGMHCEDIYRN--GGRTSEAYYIQPD-LFSEPYKVFCDMESHGGGWTVVQNRVDGSSNFARDWNTYKAEFGNIA FbE_Hu: GHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLP-GSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLN Fb2_SL: HRTNLSEYIDCLDVLQRRPGGKASGLYEVRPR-GAKRALTVHCEQDTDGGGWTLVQQREDGSLNFNRSFSAYREGFGTVD FbR_Hu: DLGSKRQYADCSEIFND--GYKLSGFYKIKPL-QSPAEFSVYCDMS-DGGGWTVIQRRSDGSENFNRGWKDYENGFGNFV T49_Hu: RPVQHLIYKDCSDYYAI--GKRSSETYRVTPD-PKNSSFEVYCDMETMGGGWTVLQARLDGSTNFTRTWQDYKAGFGNLR FbX_Ms: QPVQHLIYKDCSDHYVL--GRRSSGAYRVTPD-HRNSSFEVYCDMETMGGGWTVLQARLDGSTNFTREWKDYKAGFGNLE SCA_Dr: ---INKLPHDCSEVHTQ-----TDGLHLIAPA-GQRHPLMTHCTAD----GWTTVQRRFDGSADFNRSWADYAQGFGAPG Fic_Hu: ----LTGPRTCKDLLDR--GHFLSGWHTIYL--PDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYKQGFGSRL FiA_Po: ----LTGPRTCKELLTR--GHILSGWHTIYL--PDCQPLTVLCDMDTDGGGWTVFQRRSDGSVDFYRDWAAYKRGFGSQL FiB_Po: ----ATGPRTCKELLTR--GHFLSGWHTIYL--PDCQPLTVLCDMDTDGGGWTVFQRRSDGSVDFYRDWAAYKRGFGSQL FbA_SC: ISHSPEYPRDCYDILQSCSGQSPPSGQYYIQP-DGGNLIKVYCDMETDEGGWTVFQRRIDGTINFYRSWSYYQTGFGNLN FbL_Hu: GGLRIPFPRDCGEEMQN--GAGASRTSTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNIS TnH_Po: -----PFPRDCGEEMQN--GVSTSRTTTIFLNGNRERPLNVFCDMETDGGGWLVFQRRMDGKTDFWRDWEDYAHGFGNIS TnR_Hu: GGRVFPHPQDCAQHLMN--GDTLSGVYPIFLNGELSQKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNVE TnN_Rt: GGRVFSHPQDCAQHLMN--GDTLSGVYTIFLNGELSHKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNLE TnN_Ck: GGRVFANPQDCAQHLMN--GDTLSGVYTISINGDLSQRVQVFCDMSTDGGGWIVFQRRQNGLTDFFRKWADYRVGFGNLE TnA_Hu: --LLYPFPKDCSQAMLN--GDTTSGLYTIYLNGDKAQALEVFCDMTSDGGGWIVFLRRKNGRENFYQNWKAYAAGFGDRR TnA_Po: --LLYPFPRDCSQAMLN--GDTTSGLYTIYVNNDKAQKLEVFCDMTSDSGGWIVFLRRKNGREDFYRNWKAYAAGFGDLK TnA_Ms: --LLYPFPRDCSQAMLN--GDTTSGLYTIYINGDKTQALEVYCDMTSDGGGWIVFLRRKNGREDFYRNWKAYAAGFGDRR TnA_Ck: --LLYPYPKDCSQALLN--GEVTSGLYTIYLNGDRTQPLQVFCDMAEDGGGWIVFLRRQNGKEDFYRNWKNYVAGFGDPK Ident.: .........2*........7...81.2.6...........9.*21...239*.5.5.*.3*...*.4.9..*..9**... Conse.: --ipvptpkDCsdilnn--GgktSGlYtIyPn-dasqpllVYCDMeTDGGGWTVFQRRqDGSvDFyRnWadYkaGFGnls Res. #: .....150.......16--0.......170..-.....180.......190.......200.......210.......22 Sec.S.: ....S...SSHHHHHHT--T....EEEEE..T-T....EEEEEEEETT.EEEeEEEEESSS.S....HHHHHHHHEEE.. Non_id: +.+...++........+--...+.........-.+++........+..++.................+......+..+.. As_con: AabmAmmbbBBBbBBmm--mBammBBBmBmBm-aBammBbBbBbBmAambBBBBBBbBbmmmBaBmbmBmmBbmmbmmmB Non_id: ++++.+..+........--..+...+.+....-.+++.+.....+..++.............++...+.....+++..++ Res. #: 0...--------....230.......240.......250.......260.......270.......280.......290. FbG_Hu: PTGT--------TEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFD FbH_Hu: PTGT--------TEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFD FbG_Bo: PTGT------GNTEFWLGNEKIHLISTQSSIPYVLRIQLEDWNGRTSTADYASFKVTGENDKYRLTYAYFIGGDAGDAFD FbG_Rt: PTGT--------TEFWLGNEKNHLISMQSTIPYALRIQLKDWSGRTSTADYAMFRVGPGSDKYRLTYAYFIGGDAGDAFD FbG_Xe: PNDK--------TEFWLGNEKIHLLSTQSTIPYVMRIELEDWSNQKSTADYSTFRLGSEKDNYRFTYAYFIGGDAGDAFD FbG_SL: PTLT--------TEFWLGNEKIHLLTGQQ--AYRLRIDLTDWENTHRYADYGHFKLTPESDEYRLFYSMYLDGDAGNAFD FbB_Hu: TNTDGKNYCGLPGEYWLGNDKISQLTRMG--PTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKY-RGTAGNALM FbB_Rt: TNEDTKKYCGLPGEYWLGNDKISQLTRIG--PTELLIEMEDWKGDKVKAHYGGFTVQTEANKYQVSVNKY-KGTAGNALM FbB_Bo: TNAEGKKYCGVPGEYWLGNDRISQLTNMG--PTKLLIEMEDWKGDKVTALYEGFTVQNEANKYQLSVSKY-KGTAGNALI FbB_Ck: K-SGGKKYCDTPGEYWLGNDKISQLTKIG--PTKVLIEMEDWNGDKVSALYGGFTIHNEGNKYQLSVSNY-KGNAGNALM FbB_SL: F-GNGKSICNIPGEYWLGTKTVHQLTKQH--TQQVLFDMSDWEGSSVYAQYASFRPENEAQGYRLWVEDY-SGNAGNALL FbE_Hu: DEGE--------GEFWLGNDYLHLLTQR---GSVLRVELEDWAGNEAYAEYH-FRVGSEAEGYALQVSSY-EGTAGDALI Fb2_SL: GSGH--------GELWLGLEAMYLLAHE---DSTMRVELQGWDGAGAHAEYT-VTLRDDSKGYALQVSDY-RGTAGNALV FbR_Hu: QKH---------GEYWLGNKNLHFLTTQE--DYTLKIDLADFEKNSRYAQYKNFKVGDEKNFYELNIGEY-SGTAGDSLA T49_Hu: ------------REFWLGNDKIHLLTKSK--EMILRIDLEDFNGVELYALYDQFYVANEFLKYRLHVGNY-NGTAGDAL- FbX_Ms: ------------REFWLGNDKIHLLTKSK--EMILRIDLEDFNGLTLYALYDQFYVANEFLKYRLHIGNY-NGTAGDAL- SCA_Dr: ------------GEFWIGNEQLHHLTLDN--CSRLQVQMQDIYDNVWVAEYKRFYISSRADGYRLHIAEY-SGNASDAL- Fic_Hu: ------------GEFWLGNDNIHALTAQG--TSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNLVLGAFVEGSAGDSL- FiA_Po: ------------GEFWLGNDHIHALTAQG--TNELRVDLVDFEGNHQFAKYRSFQVADEAEKYMLVLGAFVEGNAGDSL- FiB_Po: ------------GEFWLGNDHIHALTAQG--TSELRVDLVDFEGNHQFAKYRSFQVAGEAEKYKLVLGGFLEGNAGDSL- FbA_SC: ------------TEFWLGNDNIHYLTSQG--DYELRVELNNTLGNHYYAKYNKFRIGDSFSEYLLVLGAY-SGTAGDSL- FbL_Hu: ------------GEFWLGNEALHSLTQAG--DYSIRVDLRA-GDEAVFAQYDSFHVDSAAEYYRLHLEGY-HGTAGDSM- TnH_Po: ------------GEFWLGNEALHSLTKAG--DYSLRVDLRA-GEEAVFAQYESFQVDSAAEHYRLHLEGY-HGTAGDSM- TnR_Hu: ------------DEFWLGLDNIHRITSQG--RYELRVDMRD-GQEAAFASYDRFSVEDSRNLYKLRIGSY-NGTAGDSL- TnN_Rt: ------------DEFWLGLDNYHRITAQG--RYELRVDMRD-GQEAVFAYYDKFAVEDSRSLYKLRIGGY-NGTAGDSL- TnN_Ck: ------------DEFWLGLDNIHKITSQG--RYELRIDMRD-GQEAAYAYYDKFSVGDSRSLYKLRIGDY-NGTSGDSL- TnA_Hu: ------------EEFWLGLDNLNKITAQG--QYELRVDLRD-HGETAFAVYDKFSVGDAKTRYKLKVEGY-SGTAGDSM- TnA_Po: ------------EEFWLGLDALSKITAQG--QYELRVDLRD-HGETAYAVYDRFSVGDARTRYKLKVEGY-SGTAGDSM- TnA_Ms: ------------EEFWLGLDNLSKITAQG--QYELRVDLQD-HGESAYAVYDRFSVGDAKSRYKLKVEGY-SGTAGDSM- TnA_Ck: ------------DEFWIGLENLHKISSQG--QYELRVDLRD-RGETAYAVYDKFSVGDAKTRYRLRVDGY-SGTAGDSM- Ident.: .............*3*8*1...2..3........53..1.6.......*.*..9.3......*.7....2..*.993... Conse.: ------------gEFWLGNDkIHlLTaQG--pYeLRVDLeDweGetayAdYdsFkVgdEadkYrLhvggY-sGTAGDAL- Res. #: 0...--------....230.......240.......250.......260.......270.......280.......290. Sec.S.: TTS.--------SEEE.HHHHHHHHHTSSSS.EEEEEEEEEETSEEEEEEEE..EEE.GGGTTEEE.SEEEE.TT..GGG Non_id: ....--------.+...+........+++++.........++..+.......++..+......+.............+++ As_con: mmbm--------bBBBBBBmbBbbBBmBmammBBBbBmBbBbammmBbBbBBmBmBbmmambBbBbBmmbmmmaBbbBBm Non_id: ....--------.......+......+..++......+....+......+..+..........+.+....++.+...... Res. #: ......300.......310.......320..-----.....330.---......340.......350......-.360.. FbG_Hu: GFDFGDDPSDKFFTSHNGMQFSTWDNDNDKF-----EGNCAEQDG---SGWWMNKCHAGHLNGVYYQGGTYSK-ASTPNG FbH_Hu: GFDFGDDPSDKFFTSHNGMQFSTWDNDNDKF-----EGNCAEQDG---SGWWMNKCHAGHLNGVYYQGGTYSK-ASTPNG FbG_Bo: GYDFGDDSSDKFFTSHNGMQFSTWDSDNDKY-----DGNCAEQVG---IGWWMNKCHAGHLNGVYYQGGTYSK-TSTPNG FbG_Rt: GYDFGDDPSDKFFTSHNGMHFSTWDNDNDKF-----EGNCAEQDG---SGWWMNKCHAGHLNGVYYQGGTYSK-SSTPNG FbG_Xe: GFDFGDDPSDKFYTSHNGMQFSTFDKDNDKF-----DGNCAEQDG---SGWWMNRCHAAHLNGKYYQGGTYSEADSGPSG FbG_SL: GFDFGDDPQDKFYTTHLGMLFSTPERDNDKY-----EGSCAEQDG---SGWWMNRCHAGHLNGKYYFGGNYRK-TDVEFP FbB_Hu: DGASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDG---GGWWYNRCHAANPNGRYYWGGQYTW-DMAKHG FbB_Rt: EGASQLVGENRTMTIHNGMFFSTYDRDNDGWVTTDPRKQCSKEDG---GGWWYNRCHAANPNGRYYWGGLYSW-DMSKHG FbB_Bo: EGASQLVGENRTMTIHNSMFFSTYDRDNDGWKTTDPRKQCSKEDG---GGWWYNRCHAANPNGRYYWGGAYTW-DMAKHG FbB_Ck: EGASQLYGENRTMTIHNGMYFSTYDRDNDGWLTTDPRKQCSKEDG---GGWWYNRCHAANPNGRYYWGGTYSW-DMAKHG FbB_SL: EGATQLMGDNRTMTIHNGMQFSTFDRDNDNWNPGDPTKHCSREDA---GGWWYNRCHAANPNGRYYWGGIYTK-EQADYG FbE_Hu: EGS---VEEGAEYTSHNNMQFSTFDRDADQW-----EENCAEVYG---GGWWYNNCQAANLNGIYYPGGSYDPRNNSPYE Fb2_SL: SG----VADDPELTSHGGMTFSTYDRDTDKW----SDGSCAEWYG---GGWWINACQAANLNGVYYQGGPYDPREKPPYE FbR_Hu: G---NFHPEVQWWASHQRMKFSTWDRDHDNY-----EGNCAEEDQ---SGWWFNRCHSANLNGVYYSGP-------YTAK T49_Hu: --------RFNKHYNHDLKFFTTPDKDNDRY----PSGNCGLYYS---SGWWFDACLSANLNGKYYHQ--------KYRG FbX_Ms: --------RFSRHYNHDLRFFTTPDRDNDRY----PSGNCGLYYS---SGWWFDSCLSANLNGKYYHQ--------KYKG SCA_Dr: -------------NYQQGMQFSAIDDDRDIS-----QTHCAANYE---GGWWFSHCQHANLNGRY--------------- Fic_Hu: -------------TFHNNQDFSTKDQDNDLN-----TGNCAVMFQ---GAWWYKNCHVSNLNGRYLRG--------THGS FiA_Po: -------------TSHNNSLFTTKDQDNDQY-----ASNCAVLYQ---GAWWYNSCHVSNLNGRYLGG--------SHGS FiB_Po: -------------SSHRDQFFSTKDQDNDNH-----SGNCAEQYH---GAWWYNACHSSNLNGRYLRG--------LHTS FbA_SC: -------------AYHNTMRFSTYDNDNDVY-----SINCASHSSYGRGAWWYKSCLLSNLNGQYY-----------DYS FbL_Hu: -------------SYHSGSVFSARDRDPNSL-----LISCAVSYR---GAWWYRNCHYANLNGLY-----------GSTV TnH_Po: -------------SYHSGSVFSARDRDPNNL-----LISCAVSYR---GAWWYRNCHYANLNGLY-----------GSTV TnR_Hu: -------------SYHQGRPFSTEDRDNDVA-----VTNCAMSYK---GAWWYKNCHRTNLNGKY-----------GESR TnN_Rt: -------------SYHQGRPFSTEDRDNDVA-----VTNCAMSYK---GAWWYKNCHRTNLNGKY-----------GESR TnN_Ck: -------------TYHQGRPFSTKDRDNDVA-----VTNCAMSYK---GAWWYKNCHRTNLNGKY-----------GESR TnA_Hu: -------------AYHNGRSFSTFDKDTDSA-----ITNCALSTR----GFWYRNCHRVNLMGRY-----------GDNN TnA_Po: -------------AYHNGRSFSTFDKDTDSA-----ITNCALSYK---GAFWYKNCHRVNLMGRY-----------GDNS TnA_Ms: -------------NYHNGRSFSTYDKDTDSA-----ITNCALSYK---GAFWYKNCHRVNLMGRY-----------GDNN TnA_Ck: -------------TYHNGRSFSTFDKDNDSA-----ITNCALSYK---GAFWYKNCHRVNLMGRY-----------GDNN Ident.: ...............9.1..*77.9.*18..........*3.........6*...*4..456*.*............... Conse.: -------------TyHNGMqFSTyDrDNDka-----egNCAesyg---GGWWYNnCHaaNLNGrYY-G--------gpng Res. #: ......300.......310.......320..-----.....330.---......340.......350......-.360.. Sec.S.: ....SS.THHHHHH..TT...BBTTB..SSS-----SSHHHHHHH---S.B..SSS.EEETTSB..TTSB...-..STT. Non_id: ......+.+....++................-----..+.....+---.........+..............+-++.++. As_con: BmmbmmmambmmbBbBmbBbBBBmmbmbbmb-----ambBBmbBb---BBBBBBmbBBBBBBBmbbamBaBmm-ambaab Non_id: .+...+...+.+.....++...........+-----+.....+..---......++..........+..+...-..+++. Res. #: .....370.-..--------....380.......390.......400.......410.----------------> FbG_Hu: YDNGIIWAT-WK--------TRWYSMKKTTMKIIPFNRLTIGEGQQHHLGGAKQAGDV----------------> FbH_Hu: YDNGIIWAT-WK--------TRWYSMKKTTMKIIPFNRLTIGEGQQHHLGGAKQVRPEHPAETEYDSLYPEDDL> FbG_Bo: YDNGIIWAT-WK--------SRWYSMKKTTMKIIPLNRLAIGEGQQHQLGGAKQVGVEHHVEIEYD--------> FbG_Rt: YDNGIIWAT-WK--------TRWYSMKETTMKIIPFNRLSIGDGQQHHMGGSKQVSVEHEVDVEYP--------> FbG_Xe: YDNGIIWAT-WR--------RRWYSMKSVTMKIMPLNRYGAEGQQTLGGSKKSDFENRGDF-------------> FbG_SL: YDDGIIWAT-WH--------DRWYSLKMTTMKLLPMGRDLSGHGGQQQSKGNSRGDN-----------------> FbB_Hu: TDDGVVWMN-WK--------GSWYSMRKMSMKIRPFFPQQ----------------------------------> FbB_Rt: TDDGVVWMN-WK--------GSWYSMRRMSMKIRPVFPQQ----------------------------------> FbB_Bo: TDDGVVWMN-WQ--------GSWYSMKKMSMKIRPYFPEQ----------------------------------> FbB_Ck: TDDGIVWMN-WK--------GSWYSMKKMSMKIKPYFPD-----------------------------------> FbB_SL: TDDGVVWMN-WK--------GSWYSMRQMAMKLRPKWP------------------------------------> FbE_Hu: IENGVVWVS-FR--------GADYSLRAVRMKIRPLVTQ-----------------------------------> Fb2_SL: VENGVVWAT-YR--------GSDYSLKRTAVRFRRVQIPIVE--------------------------------> FbR_Hu: TDNGIVWYT-WH--------GWWYSLKSVVMKIRPNDFIPNVI-------------------------------> T49_Hu: VRNGIFWGT-WPGVSEAHPGGYKSSFKEAKMMIRPKHFKP----------------------------------> FbX_Ms: VRNGIFWGT-WPGINQAQPGGYKSSFKQAKMMIRPKNFKP----------------------------------> SCA_Dr: -NLGLTWFDAAR--------NEWIAVKSSRMLVKRL--------------------------------------> Fic_Hu: FANGINWKS-GK--------GYNYSYKVSEMKVRPA--------------------------------------> FiA_Po: FANGVNWSS-GK--------GYNYSYKVSEMKFRAT--------------------------------------> FiB_Po: YANGVNWRS-GR--------GYNYSYQVSEMKVRLT--------------------------------------> FbA_SC: GAPSIYWSY-LP--------GDNDQIPFAEMKLRNRSI------------------------------------> FbL_Hu: DHQGVSWYH-WK--------GFEFSVPFTEMKLRPRNFRSPAGGG-----------------------------> TnH_Po: DHQGVSWYY-WK--------GFEFSVPFTEMKLRPRSFRPPGRGG-----------------------------> TnR_Hu: HSQGINWYH-WK--------GHEFSIPFVEMKMRPYNHRLMAGRKRQSLQF-----------------------> TnN_Rt: HSQGINWYH-WK--------GHEFSIPFVEMKMRPYIHRLTAGRKRRALKF-----------------------> TnN_Ck: HSQGINWYH-WK--------GHEFSIPFVEMKMRPYNHRNISGRKRRSLQL-----------------------> TnA_Hu: HSQGVNWFH-WK--------GHEHSIQFAEMKLRPSNFRNLEGRRKRA--------------------------> TnA_Po: HSQGVNWFH-WK--------GHEYSIQFAEMKLRPSNFRNLEGRRKRA--------------------------> TnA_Ms: HSQGVNWFH-WK--------GHEYSIQFAEMKLRPSNFRNLEGRRKRA--------------------------> TnA_Ck: HSQGVNWFH-WK--------GHEYSIQFAEMKLRPSSFRNLEGRRKRA--------------------------> Ident.: ...9..*...3.........3...8.....96.25.......................................> Conse.: hdnGinWat-WK--------GhwYSmkfteMKiRPynfr-----------------------------------> Res. #: .....370.-..--------....380.......390.......400.......410.----------------> Sec.S.: ...BSEEET-TS--------.TTB..SEEEEEEEE...............------------------------> Non_id: .......+.-..--------...............++++-----------------------------------> As_con: mbbBBBBBm-bb--------mbbBBBmmBBBBBBBbmbA-----------------------------------> Non_id: +.+......-..--------...+..+.........+++----------------------------------->