The Blob Page
The program Blob is intended as an aid in interpreting density.
Blob uses a Metropolis Monte Carlo simulated annealing
algorithm to optimize molecules in electron density. We have used
Blob in a variety of ways. These include:
- Positioning small flexible ligands into electron density maps from
- Positioning ideal DNA
fragments into electron density maps from protein-DNA complexes.
- Positioning entire protein domains into electron density maps
from multi-domain protein.
A Short Introduction to Blob - the manual
Generally speaking the postscript version will be the most complete and
up to date.
The Blob executables are now freely available.
Download Blob0.tar.Z . Then
This should create a directory named Blob0 with all the necessary files
in it. Happy Blobbing.
- uncompress Blob0.tar.Z
- tar xvf Blob0.tar
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Biological Structure Center
Health Sciences Center, K-454
University of Washington
Seattle, WA 98195-7742
Think globally. Act locally...... Integrate by Parts.